- Title
- Shutting the gate: targeting endocytosis in acute leukemia
- Creator
- Tremblay, Cedric S.; Ting, Stephen B.; McCluskey, Adam; Robinson, Phillip J.; Curtis, David J.
- Relation
- Experimental Hematology Vol. 104, Issue December 2021, p. 17-31
- Publisher Link
- http://dx.doi.org/10.1016/j.exphem.2021.09.003
- Publisher
- Elsevier
- Resource Type
- journal article
- Date
- 2021
- Description
- Endocytosis entails selective packaging of cell surface cargos in cytoplasmic vesicles, thereby controlling key intrinsic cellular processes as well as the response of normal and malignant cells to their microenvironment. The purpose of this review is to outline the latest advances in the development of endocytosis-targeting therapeutic strategies in hematological malignancies.
- Subject
- endocytosis; leukemia; cells; microenvironment
- Identifier
- http://hdl.handle.net/1959.13/1435074
- Identifier
- uon:39597
- Identifier
- ISSN:0301-472X
- Language
- eng
- Reviewed
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